Noni Juice And Liver Failure

Over the last two decades, a growing number of people have become interested in the medicinal uses of Noni juice, made from the fruit of the Indian mulberry (Morinda Citrifolia) of the South Pacific Islands of Tahiti, and more recently from Hawaii. Noni has been used in folk remedies by Polynesians for over 2000 years, and is reported to have a broad range of therapeutic effects, including antibacterial, antiviral, antifungal, antitumor, antihelminth, analgesic, hypotensive, anti-inflammatory, and immune enhancing effects. Noni juice is also promoted to enhance energy and wellbeing. On the other hand, there are talk of noni juice side effects like liver failure.

Noni has been documented to contain a mixture of anthraquinones, organic acids, xeronine, several vitamins (such as beta-carotene, niacin, riboflavin, thiamine), some minerals, iron and calcium. The potassium content of Noni is similar to that in tomato juice and orange juice. Besides that Noni juice is beneficial to cure cancer, diabetes, high cholesterol, obesity, arthritis and other health conditions.

Although Noni juice is beneficial in many ways, still it is undeniable that it comes with some side effects. Hawaii is home to the growers of Noni juice. Noni has had some cases of harm to kidneys according to the growers of Noni juice. They suggested people with history of both kidney and liver diseases should avoid Noni. Noni is very high in potassium and has been a cause of very high potassium levels. Lemon juice is a great flush, low in potassium, cheaper to obtain, and makes one alkaline. There are several cases in the literature that link Noni to inflamed livers (hepatitis).

There have been two reported cases in the medical literature (both in Austria) regarding liver damage due to excessive Noni juice consumption. As with any herb, it is best to use low amounts. It is preferred to use small amounts of different herbs as opposed to a large amount of a single herb. It is also known that some herbs are healthy to ingest in small amounts, yet they have a potential to be harmful if used in excessive dosages (noni juice dosage). There is a possibility that Noni itself was not the problem in these cases, but something else in the juice.

In addition, routine laboratory tests and trans jugular or percutaneous liver biopsy were performed. The first patient underwent successful liver transplantation while the second patient recovered spontaneously after cessation of Noni juice. A 29-year-old man with previous toxic hepatitis associated with small doses of paracetamol developed sub-acute hepatic failure following consumption of 1.5 litres Noni juice over three weeks necessitating urgent liver transplant. While a 62-year-old woman without evidence of previous liver disease developed an episode of self-limited acute hepatitis following consumption of 2 liters Noni juice for over 3 months. The most likely hepatotoxic components of Morinda Citrifolia were anthraquinones. Physicians should be aware of potential hepatotoxicity of Noni juice.

Another example of liver failure due to an excessive use of Noni juice is the taken from Department of Internal Medicine II, Ludwig Maximilians University of Munich, Germany, A 24-year-old female patient presented to her community hospital with mild elevations of serum transaminase and bilirubin levels. Because of multiple sclerosis, she was treated with interferon beta-1a for 6 weeks. After exclusion of viral hepatitis due to hepatitis A-E, interferon beta-1a was withdrawn under the suspicion of drug-induced hepatitis. One week later, she was admitted again to her community hospital with severe icterus. The transaminase and bilirubin levels were highly elevated, and a beginning impairment of the liver synthesis was expressed by a reduced prothrombin time. The confinement to our department occurred with a fulminant hepatitis and the suspicion of beginning acute liver failure. There was no evidence for hepatitis due to potentially hepatotoxic viruses, alcoholic hepatitis, Budd-Chiari syndrome, hemochromatosis, and Wilson's disease. In her serum there were high titers of liver-kidney microsomal type 1 autoantibody; the serum gamma globulin levels were in the normal range. Fine-needle aspiration biopsy of the liver ruled out an autoimmune hepatitis but showed signs of drug-induced toxicity. During the interview, she admitted that for 'general immune system stimulation' she had been drinking Noni juice, a Polynesian herbal remedy made from a tropical fruit (Morinda Citrifolia), during the past 4 weeks. After cessation of the Noni juice ingestion, her transaminase levels normalized quickly and were in the normal range within 1 month.

All in all, the usage of Noni juice can be considered safe if it is not being over used by people. So to be safe make sure that you have your doctor’s advice before trying or used any kinds of product made from Noni juice to avoid possible liver failure or other problems.

04.06.2008. 01:25


anonymous 30.09.2009. 20:55

i think this is a huge scam trying to make big money off people. This won't even post.

Erin L. 17.05.2010. 03:31

I use noni juice as a recomendation from my nutritionist, and it works wonders for my depression. Took myself off of all medicines *because I was sick of side effects. This Noni has no side effects for me except making me feel great, more energy and generally feeling good for a change! What a surprise. I really feel it if I stop taking it. will continue, and hope it provides other benefits like weight loss.

Laura R 03.02.2011. 15:19

I absolutely believe in Noni Juice. It makes me feel so much more alive! I have more energy and vitality. It is worth every dime to me. I am thankful for this fruit.

E K 14.06.2011. 07:48


Anonymous 26.10.2011. 03:27

i was wondering if noni is known to have any effect on fibroid growth in women...thanks all the same, this has been very educative..

Aron 06.11.2011. 00:50

I just started noni juice about one week ago. Anyone here drinkers of the juice?

Aron 06.11.2011. 00:52

I just started noni juice about one week ago. Anyone here drinkers of the juiceIf so please give your information about when you first started taking noni juice.

farrah 27.06.2012. 20:53

My friend been taking noni juice he had cancer now he is doing good thanks God prayer and noni juice.

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